Thanks for the reply.
I disabled Universal AV, then tried test. Still slow. I disabled Offline AV, tried test. Still slow.
I enabled Offline and Universal, then disabled Real time scanning...it was snappy. I even tried to disable all but 2 AV engines (not sure if this would help or not), still slow.
All I have to test this on is 2 clean copies of Windows 10. Both i7 systems. Not sure if this is related to Windows 10 and the software since I don't have a Windows 7, 8.1 system to test this on.
I am opening chrome as a reference test for performance. On both systems, with Real time scanning enabled, chrome opens fully in 6 secs. Disabled, it opens in 3 secs. This is repeatable many times.
Update: I tried something else. I tested opening speed on a PDF doc with Real Time Scanning enabled WHILE adding an exclusion for the PDF. Nothing changed. Maybe the exclusions are for on demand scans only.